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Is diphenhydramine or doxylamine better for sleep? Doxylamine succinate is one of the most sedating antihistamines available over-the-counter (stronger than diphenhydramine). A single dose causes rapid and marked drowsiness in the vast majority of individuals. Doxylamine succinate is eliminated somewhat more slowly from the body than diphenhydramine hydrochloride.
Can doxylamine succinate keep you awake? Doxylamine succinate (Unisom SleepTabs) is another antihistamine used to treat insomnia. Though antihistamine sleep aids are marketed as non-habit-forming, individuals may develop a tolerance to them and abuse them for their sedative effects.
How much ZzzQuil can kill you? A 12oz. bottle of zzzQuil has 11.8 doses, or 590mg of diphenhydramine. So, if you weigh 60kg or less, a whole bottle might kill you. Note, you don't 'sleep yourself to death' - you go into cardiovascular collapse. It's probably not an elegant method of suicide.
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